What You Need to Know About
Abilify Drug Interactions

Abilify drug interactions should be considered and understood when taking this medication. According to the manufacturer and the comprehensive label there are some drugs that can affect Abilify - also known as Aripiprazole. And Aripiprazole can affect other drugs.

Other Drugs That Affect Abilify

  • Ketaconazole - May increase concentrations of Arapiprazole. If taking both, the dosage of the aripiprazole should be reduced to 50% of what is normally prescribed. Other inhibitors such as itraconazole will have similar effects, thus also require a reduction in the dose of Aripiprazole that is taken. Once these inhibitors are no longer being taken, the aripiprazole dose can be increased back to the recommended dosage.

  • Quinidine, Fluoxetine and Paroxetine – May cause increased aripiprazole plasma levels, potentially increasing the risk of side effects. Again, the aripiprazole dose should be cut in half when taking these inhibitors concurrently. Increase the does once the inhibitors are no longer being taken. The only exception is when these inhibitors are being taken by patients with major depressive disorders. In this case, no dosage adjustment is necessary.

  • Carbamazepine – When taken with Abilify, a decrease in aripiprazole concentrations may be experienced. As a result, the Abilify dosage should be doubled. When carbamazepine is discontinued the Abilify dosage should be reduced.

    Abilify’s Affects on Other Drugs

    Based on studies about Abilify drug interactions, there is a low probability of Abilify causing any clinical interactions with drugs metabolized by cytochrome P450 enzymes.

  • Alcohol – As with most antipsychotic medications, it is not recommended that a patient consume alcohol while taking antipsychotic meds.

    Minimal / Non-existent Abilify Drug Interactions

    The list below includes drugs that did not interact with aripiprazole, thus no changes were necessary to the prescribed dose when taken with the list of drugs below:

  • Famotidine
  • Valproate
  • Lithium
  • Lamotrigine
  • Dextromethorphan
  • Warfarin
  • Omeprazole
  • Lorazepam
  • Escitalopram
  • Venlafaxine As you can see there are a lot of things to consider when taking medications. Once you understand how they interact and affect each other, you can make informed decisions about what to take and when to take it. This ensures that you reap the benefits of what you are taking and that they do what they are suppose to do. Unfortunately, there are a lot of accidental deaths out there because they mixed drugs that didn't interact well with each other, leading to tragedy. If people would take the tine to educate themselves (like you are doing!) they can avoid this. So I applaud you for taking that step and learning more. If you want to learn more about this medication, my related articles below:
  • What is Abilify?
  • Abilify Side Effects - What You Need To Know
  • What is the Right Abilify Dosage?
  • A Popular Question: Does Abilify Cause Weight Gain?
  • Learn more about Abilify Medication
  • Abilify and pregancy?
  • Abilify withdrawal
  • In addition to Abilify drug interactions, I invite you to read some general information about how depression medications work. Have you had success learning how to fight depression and win? Share your strategy with others and teach them how to overcome depression.

    Also, if you'd like some support so that you can leave depression behind and live a happy, vibrant life again please schedule a consultation with me by clicking on the image at the top right of this page!  Let's talk! There is hope! There is help!


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